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While chronic kidney disease is a progressive disease, in many cases it is possible to detect the disease before the onset of clinical symptoms, when the remaining functional renal mass is less than 25% of normal, corresponding to IRIS stages 3 and above.
Measurement of SDMA, in conjunction with serum creatinine concentration and repeated over time, can provide valuable information regarding a patient’s glomerular filtration rate.
The information gained from evaluation of a minimum database is valuable for pets of all ages. As the prevalence of CKD increases significantly with age, especially in cats, it is prudent to monitor renal function annually in cats starting at about 7 years old.