Research on the key nutrients in support of the skin barrier

What has Royal Canin Research found previously about Canine Atopic Dermatitis (CAD) - particularly regarding the skin barrier?

Royal Canin has leveraged research conducted at the Waltham Centre on key nutrients such as B vitamins, pantothenic acid, niacin, choline, histidine, and certain amino acids, which have shown benefits for the skin barrier both in vitro and in vivo. Recent work by external researchers, including Juliana Popa, showed dogs who are fed diets high in linoleic acid showed increased levels of both linoleic acid and ceramides in the stratum corneum, further supporting skin barrier health. Collaborative studies with Waltham confirmed combining linoleic acid, an Omega-6 polyunsaturated fatty acid, with zinc enhances skin barrier properties.

What are the key nutrients of the skin barrier complexes and how do they assist in managing CAD?

Animals with atopic conditions often have a compromised skin barrier, allowing allergens to penetrate and trigger immune responses in sensitive pets. Therefore, it can be advantageous to include supporting the skin barrier in a comprehensive management plan for the diseases. This was highlighted during the European Congress of Dermatology in September 2021 where Dr. Cecilia Villaverde emphasized the importance of a complete and balanced diet, given the size and turnover of the skin as an organ. She also noted that linoleic acid is vital for skin barrier function, because it contributes to the formation of intercellular lipids in the stratum corneum, along with other essential nutrients like B vitamins, niacin, pantothenic acid, choline, zinc, and antioxidants.

Is there an ideal amount or ration of Omega 3 : Omega 6 fatty acids to help manage CAD?

Oral polyunsaturated fatty acids have shown beneficial effects in several diseases such as osteoarthritis or inflammatory skin issues. In the Omega 6 family, gamalinolenic acid (GLA) is a nutrient that can support pets' coat quality. In the Omega 3 family, EPA and DHA have demonstrated benefits.

Is there an overlap between the treatment of Adverse food reactions (AFR) and CAD?

Is there a way to treat both conditions with one diet without the need for an elimination diet trial?

The clinical skin signs of AFR and CAD may appear quite similar. However, it’s important to identify the underlying cause of skin issues through a food elimination trial, as treatments can differ significantly. Knowing the root cause can help pet owners determine if their dog can safely enjoy occasional treats or if desensitization to specific environmental allergens is worth considering.

To learn more, watch the full video!